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Protective Effects of Inducible HO-1 on Oxygen Toxicity in Rat Brain Endothelial Microvessel Cells

BackgroundReperfusion in ischemia is believed to generate cytotoxic oxidative stress, which mediates reperfusion injury. These stress conditions can initiate lipid peroxidation and damage to proteins, as well as promote DNA strand breaks. As biliverdin and bilirubin produced by heme oxygenase isofor...

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Principais autores: Seung-Jun Yoo, Neal K. Nakra, Gabriele V. Ronnett, Cheil Moon
Format: Artigo
Sprog:Inglês
Udgivet: Korean Endocrine Society 2014-09-01
Serier:Endocrinology and Metabolism
Fag:
Heme
Oxygenases
Bilirubin
Iron
Carbon monoxide
Online adgang:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-356.pdf
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