Genomic instability as a driver and suppressor of anti-tumor immunity

Genomic instability is a driver and accelerator of tumorigenesis and influences disease outcomes across cancer types. Although genomic instability has been associated with immune evasion and worsened disease prognosis, emerging evidence shows that genomic instability instigates pro-inflammatory sign...

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Principais autores:	Marta Requesens, Floris Foijer, Hans W. Nijman, Marco de Bruyn
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2024-10-01
Serija:	Frontiers in Immunology
Teme:	genomic instability MMRd chromosomal instability cGAS-STING tumor-infiltrating lymphocytes immune evasion
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1462496/full
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