LGR signaling mediates muscle-adipose tissue crosstalk and protects against diet-induced insulin resistance

Abstract Obesity impairs tissue insulin sensitivity and signaling, promoting type-2 diabetes. Although improving insulin signaling is key to reversing diabetes, the multi-organ mechanisms regulating this process are poorly defined. Here, we screen the secretome and receptome in Drosophila to identif...

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主要な著者:	Olga Kubrak, Anne F. Jørgensen, Takashi Koyama, Mette Lassen, Stanislav Nagy, Jacob Hald, Gianluca Mazzoni, Dennis Madsen, Jacob B. Hansen, Martin Røssel Larsen, Michael J. Texada, Jakob L. Hansen, Kenneth V. Halberg, Kim Rewitz
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2024-07-01
シリーズ:	Nature Communications
オンライン･アクセス:	https://doi.org/10.1038/s41467-024-50468-w
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