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Assessment of the efficacy of various neoadjuvant anti-HER2 targeted therapies combined with chemotherapy for HER2-positive breast cancer in the real-world setting and development of a predictive model for pathological complete response

BackgroundThe development of a robust and clinically applicable predictive model for pathological complete response (pCR) following neoadjuvant therapy (NAT) in human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) is of critical importance.MethodsIn this retrospective study, 3...

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Principais autores: Haoqi Wang, Shan Gao, Zihao Bai, Lijia Wang, Cuizhi Geng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-11-01
coleção:Frontiers in Oncology
Assuntos:
real world
HER2-positive breast cancer
neoadjuvant therapy
different anti-HER2 targeted therapies
pathological complete response
nomogram
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2025.1673810/full
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