Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and invadopodia formation, establishing it as a pivotal therapeutic target. Herein, copper‐paeonol nanozymes (CuPaeNs) is engineered through metal‐pheno...

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Hauptverfasser:	Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2026-03-01
Schriftenreihe:	Advanced Science
Schlagworte:	actin‐bundling activity catalytic therapy fascin metal‐phenolic nanozymes tumor metastasis
Online-Zugang:	https://doi.org/10.1002/advs.202512186
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