Accumulation of sequence variants in genes of Wnt signaling and focal adhesion pathways in human corneas further explains their involvement in keratoconus

Background Keratoconus (KTCN) is a protrusion and thinning of the cornea, resulting in loss of visual acuity. The etiology of KTCN remains unclear. The purpose of this study was to assess the potential involvement of new genetic variants in KTCN etiology based on both the genomic and transcriptomic...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Justyna A. Karolak, Tomasz Gambin, Malgorzata Rydzanicz, Piotr Polakowski, Rafal Ploski, Jacek P. Szaflik, Marzena Gajecka
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	PeerJ Inc. 2020-04-01
Цуврал:	PeerJ
Нөхцлүүд:	Candidate keratoconus gene Overrepresentation analysis Corneal disease Keratoconus genetics WNT signaling Focal adhesion
Онлайн хандалт:	https://peerj.com/articles/8982.pdf
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!