P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells

Abstract Background Gastric cancer (GC), a prevalent aggressive form of tumor, imposes a significant burden in terms of morbidity and mortality. Prolyl 4-hydroxylase, alpha polypeptide I (P4HA1), a key enzyme in collagen synthesis, comprises two identical alpha subunits and two beta subunits. Studie...

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Detalhes bibliográficos

Principais autores:	PeiYao Gao, HengJin Tian, KunPeng Ge, FeiFan Wang, YanMing Zhao, JiWen Sun, Qiang Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2025-04-01
coleção:	Discover Oncology
Assuntos:	Gastric cancer Proline 4-hydroxylase 1 Proliferation Migration Stemness
Acesso em linha:	https://doi.org/10.1007/s12672-025-02337-1
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