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Isothermal microcalorimetry measures UCP1-mediated thermogenesis in mature brite adipocytes

Bokhari et al. demonstrate mature murine brown and brite adipocytes produce quantifiable heat with β3-AR stimulation. They indicate that the essential component of this mechanism is UCP1 by using adipocytes lacking the protein.

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Principais autores: Muhammad Hamza Bokhari, Carina Halleskog, Alice Åslund, Nathalie Boulet, Eva Casadesús Rendos, Jasper Martin Anton de Jong, Robert Csikasz, Ez-Zoubir Amri, Irina Shabalina, Tore Bengtsson
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2021-09-01
Serier:Communications Biology
Online adgang:https://doi.org/10.1038/s42003-021-02639-4
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