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Optimization of luspatercept treatment for beta-thalassemia transmission control using pure fraction mathematical modeling

Background: Beta-thalassemia is a prevalent genetic blood disorder characterized by reduced hemoglobin production leading to systemic hypoxia. Understanding and controlling its transmission dynamics is crucial for effective management. This study aims to analyze mathematical frameworks for mitigatin...

Ausführliche Beschreibung

Gespeichert in:
1. Verfasser: Sapna Ratan Shah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Medknow Publications 2025-01-01
Schriftenreihe:Advances in Biomedical and Health Sciences
Schlagworte:
beta-thalassemia
compartmental models
genetic blood disorder
hemoglobin synthesis
high-risk populations
hypoxia
mathematical modeling
pure fraction method
targeted interventions
Online-Zugang:https://journals.lww.com/abhs/fulltext/2025/01000/optimization_of_luspatercept_treatment_for.3.aspx
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