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Distinct Roles of PKCι/λ and PKMζ in the Initiation and Maintenance of Hippocampal Long-Term Potentiation and Memory

PKMζ has been proposed to be essential for maintenance of long-term potentiation (LTP) and long-term memory (LTM). However, recent data from PKMζ-knockout mice has called this role into question. Instead, the other atypical isoform, protein kinase C iota/lambda (PKCι/λ), has emerged as a potential a...

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Hlavní autoři: Shaoli Wang, Tao Sheng, Siqiang Ren, Tian Tian, Wei Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016-08-01
Edice:Cell Reports
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211124716309482
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