Altering VP1 and VP2 expression in trans affects the transduction efficiency of AAV9

Currently, adeno-associated virus (AAV) is one of the most reliable carrier for gene delivery in both proliferating and non-proliferating cells. Stable and long-lasting transgene expression has made this viral vector a key platform for the development of advanced therapy. Nevertheless, the widesprea...

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Auteurs principaux:	Maxim K. Efremov, Alima Galieva, Andrew N. Brovin, Natalia V. Mesonzhnik, Mikhail B. Afonin, Elena N. Subcheva, Alexander Karabelsky
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-02-01
Collection:	Frontiers in Bioengineering and Biotechnology
Sujets:	aav adeno-associated virus capsid engineering capsid stoichiometry gene therapy transduction efficiency
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fbioe.2026.1753246/full
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