Sex differences in the neuronal transcriptome and synaptic mitochondrial function in the cerebral cortex of a multiple sclerosis model

IntroductionMultiple sclerosis (MS) affects the cerebral cortex, inducing cortical atrophy and neuronal and synaptic pathology. Despite the fact that women are more susceptible to getting MS, men with MS have worse disability progression. Here, sex differences in neurodegenerative mechanisms are det...

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Autors principals:	Noriko Itoh, Yuichiro Itoh, Linsey Stiles, Rhonda Voskuhl
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-11-01
Col·lecció:	Frontiers in Neurology
Matèries:	multiple sclerosis experimental autoimmune encephalomyelitis sex differences mitochondria cerebral cortex RNA sequencing
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fneur.2023.1268411/full
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