Case report of adult-type diffuse high-grade glioma IDH-wildtype subtype E with secondary spinal leptomeningeal dissemination, prolonged survival and literature review

Abstract Objectives We report the case of an adult-type diffuse glioma with spinal leptomeningeal dissemination, corresponding to a new molecularly methylation class, identified as "Adult-type diffuse high-grade glioma, IDH-wildtype, subtype E," using the Heidelberg Epignostix CNS Tumor Classifier v...

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Autori principali:	Adèle Meola, Romain Appay, Benoit Testud, Gregorio Petrirena, Chantal Campello, Maryline Barrié, Alexandre Bertucci, Didier Autran, Thomas Graillon, Kaissar Farah, Laetitia Padovani, Isabelle Pougnet, Isabelle Nanni, Olivier Chinot, Emeline Tabouret, Vincent Harlay
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2026-05-01
Serie:	Discover Oncology
Soggetti:	Glioblastoma Methylation profiling Spinal leptomeningeal dissemination Bevacizumab Long-term survival
Accesso online:	https://doi.org/10.1007/s12672-026-04979-1
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