Dexrazoxane does not mitigate early vascular toxicity induced by doxorubicin in mice.
Apart from cardiotoxicity, the chemotherapeutic agent doxorubicin (DOX) provokes acute and long-term vascular toxicity. Dexrazoxane (DEXRA) is an effective drug for treatment of DOX-induced cardiotoxicity, yet it remains currently unknown whether DEXRA prevents vascular toxicity associated with DOX....
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science (PLoS)
2023-01-01
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| Schriftenreihe: | PLoS ONE |
| Online-Zugang: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294848&type=printable |
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