RIG-I is responsible for activation of type I interferon pathway in Seneca Valley virus-infected porcine cells to suppress viral replication

Abstract Background Retinoic acid-inducible gene I (RIG-I) is a key cytosolic receptor of the innate immune system. Seneca valley virus (SVV) is a newly emerging RNA virus that infects pigs causing significant economic losses in pig industry. RIG-I plays different roles during different viruses infe...

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Hlavní autoři:	Pengfei Li, Xiangle Zhang, Weijun Cao, Fan Yang, Xiaoli Du, Zhengwang Shi, Miaotao Zhang, Xiangtao Liu, Zixiang Zhu, Haixue Zheng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2018-10-01
Edice:	Virology Journal
Témata:	RIG-I SVV Interferon Immune response Viral replication
On-line přístup:	http://link.springer.com/article/10.1186/s12985-018-1080-x
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