Nebulized bone marrow-derived stem cell supernatant induces tolerogenic dendritic cells via upregulation of FOXO3 for EAE treatment

Abstract Background Bone marrow mesenchymal stem cells (BMSCs) exert potent paracrine effects that can reshape the immune microenvironment. Nebulized inhalation enables non-invasive, targeted delivery to the lung, a pivotal immune interface capable of modulating systemic immunity. This study introdu...

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Bibliografiske detaljer

Principais autores:	Junfeng Wu, Zhixin Qiao, Yanping Wang, Sifan Zhang, Jiayu Ji, Xiaoru Ma, Xiyu Zhang, Xin Xiu, Xiujuan Lang, Xijun Liu, Bo Sun, Hulun Li, Yumei Liu
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2026-01-01
Serier:	Journal of Neuroinflammation
Fag:	Stem cell supernatant Experimental autoimmune encephalomyelitis Dendritic cell Antigen presentation FOXO3
Online adgang:	https://doi.org/10.1186/s12974-025-03690-2
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