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Preoperative phenotypic stratification of primary central nervous system lymphoma using multiparametric MRI-based radiomics: prediction of germinal center B-cell-like and double-expression status

BackgroundPrimary central nervous system lymphoma (PCNSL) exhibits substantial biological heterogeneity, particularly across immunohistochemical subtypes such as double-expression lymphoma (DEL) and germinal center B-cell-like (GCB) phenotypes. This study aimed to develop and evaluate multiparametri...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Lingxu Chen, Xiaochen Wang, Sihui Wang, Tong Chen, Xuening Zhao, Ying Yan, Mengyuan Yuan, Shengjun Sun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-06-01
Schriftenreihe:Frontiers in Oncology
Schlagworte:
del
germinal center
MRI
primary cns lymphoma
radiomics
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fonc.2026.1822040/full
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