Edoxaban pharmacokinetics during in vitro continuous renal replacement therapy

Abstract Background To evaluate the clearance of edoxaban during modeled in vitro continuous renal replacement therapy (CRRT), assess protein binding and circuit adsorption, and provide initial dosing recommendations. Methods Edoxaban was added to the CRRT circuit and serial pre-filter bovine blood...

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Autores principales:	Eric Wenzler, Kaitlyn Dalton, Lauren Andrews, Scott T. Benken
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-10-01
Colección:	BMC Nephrology
Materias:	Edoxaban Pharmacokinetics Dialysis Renal replacement therapy Sieving coefficient Saturation coefficient
Acceso en línea:	https://doi.org/10.1186/s12882-024-03777-7
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