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JC virus T-antigen regulates glucose metabolic pathways in brain tumor cells.

Recent studies have reported the detection of the human neurotropic virus, JCV, in a significant population of brain tumors, including medulloblastomas. Accordingly, expression of the JCV early protein, T-antigen, which has transforming activity in cell culture and in transgenic mice, results in the...

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Autors principals: Evan Noch, Ilker Kudret Sariyer, Jennifer Gordon, Kamel Khalili
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3322159?pdf=render
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