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A case of karyomegalic interstitial nephritis without FAN1 mutations in the setting of brentuximab, ifosfamide, and carboplatin exposure

Abstract Background Karyomegalic interstitial nephritis (KIN) is a rare renal diagnosis associated with both genetic and medication etiologies. The primary gene associated with KIN is the FAN1 gene which encodes a protein responsible for DNA interstrand repair. Common medication triggers of KIN are...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Matthew Leong, Tiane Dai, Lili Tong, Cynthia C. Nast
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2024-11-01
Rangatū:BMC Nephrology
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12882-024-03689-6
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