LR Hunting: A Random Forest Based Cell–Cell Interaction Discovery Method for Single-Cell Gene Expression Data

Cell–cell interactions (CCIs) and cell–cell communication (CCC) are critical for maintaining complex biological systems. The availability of single-cell RNA sequencing (scRNA-seq) data opens new avenues for deciphering CCIs and CCCs through identifying ligand-receptor (LR) gene interactions between...

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Κύριοι συγγραφείς:	Min Lu, Yifan Sha, Tiago C. Silva, Antonio Colaprico, Xiaodian Sun, Yuguang Ban, Lily Wang, Brian D. Lehmann, X. Steven Chen
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2021-08-01
Σειρά:	Frontiers in Genetics
Θέματα:	random forests ligand-receptor interaction cell–cell interaction cell–cell communications single-cell RNA-seq
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fgene.2021.708835/full
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