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rRNA transcription is integral to phase separation and maintenance of nucleolar structure.

Transcription of ribosomal RNA (rRNA) by RNA Polymerase (Pol) I in the nucleolus is necessary for ribosome biogenesis, which is intimately tied to cell growth and proliferation. Perturbation of ribosome biogenesis results in tissue specific disorders termed ribosomopathies in association with altera...

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Podrobná bibliografie
Hlavní autoři: Soma Dash, Maureen C Lamb, Jeffrey J Lange, Mary C McKinney, Dai Tsuchiya, Fengli Guo, Xia Zhao, Timothy J Corbin, MaryEllen Kirkman, Kym Delventhal, Emma L Moore, Sean McKinney, Rita Shiang, Paul A Trainor
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2023-08-01
Edice:PLoS Genetics
On-line přístup:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010854&type=printable
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