Anti-oxidative stress therapies prevent severe chemotherapy-induced peripheral neuropathy in colorectal cancer patients treated with oxaliplatin: a systematic review and meta-analysis

Background and purposeChemotherapy-induced peripheral neuropathy (CIPN) is a major side-effect of many commonly used cancer drugs, affecting up to 90% of patients treated with oxaliplatin. This systematic review and meta-analysis analysed randomised controlled trials (RCTs) to determine if any pharm...

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Autori principali:	Mohamed Salama, David Barnes, Anni Georghiou, Mariam Murad, Seham Almalki, Zubair Ahmed, Mark R. Openshaw, Claire Palles, Richard I. Tuxworth
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-09-01
Serie:	Frontiers in Oncology
Soggetti:	bowel cancer CIPN platinum agents neurotoxicity oxidative stress
Accesso online:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1642552/full
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