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Omecamtiv mecarbil in precision-cut living heart failure slices: A story of a double-edged sword

Heart failure (HF) is a rapidly growing pandemic while medical treatment options remain limited. Omecamtiv mecarbil (OM) is a novel HF drug that directly targets the myosin heads of the cardiac muscle. This study used living myocardial slices (LMS) from patients with HF to evaluate the direct biomec...

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Principais autores: Jorik H. Amesz, Sanne J.J. Langmuur, Mark F.A. Bierhuizen, Natasja M.S. de Groot, Olivier C. Manintveld, Yannick J.H.J. Taverne
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2023-09-01
Serija:Journal of Molecular and Cellular Cardiology Plus
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2772976123000107
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