Structural Identification of Impurities in Pioglitazone Hydrochloride Preparations by 2D-UHPLC-Q-Exactive Orbitrap HRMS and Their Toxicity Prediction

Pharmaceutical companies and regulatory agencies have more and more concerns for impurities in pharmaceuticals and their toxicity. In this work, heart-cutting two-dimensional ultrahigh-performance liquid chromatography (2D-UHPLC) in combination with high-resolution mass spectrometry (HRMS) was used,...

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Bibliografische gegevens

Hoofdauteurs:	Dandan Zhang, Weijian Wang, Haiyun Zhao, Song Wang, Mingyan Yu, Dongmei Zhang, Wenkun Liu, Qiangsheng Xie, Dejun Chen
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2023-01-01
Reeks:	International Journal of Analytical Chemistry
Online toegang:	http://dx.doi.org/10.1155/2023/2096521
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