New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Endocrine disruptors (EDs) are implicated in adverse developmental and reproductive outcomes, yet their identification remains a major challenge in chemical safety assessment. Current testing strategies rely heavily on animal models, which are constrained by ethical concerns, interspecies difference...

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Bibliografiske detaljer

Principais autores:	Jacob Ardenkjær-Skinnerup, Yoni Baert, Lola Bajard, Jonathan Blum, François Brion, Lucia Coppola, Jean-Baptiste Fini, Ellen Fritsche, Henrik Holbech, Selma Hurem, Miriam Naomi Jacobs, Hanna Katarina Lilith Johansson, Dries Knapen, Katharina Koch, Jan Ludvig Lyche, Phuong Ngoc Thi Mai, Winfried Neuhaus, Nikolai Georgiev Nikolov, Atika Nurani, Katerina Papageorgiou, Rikke Poulsen, Louise Ramhøj, Eliška Řehůřková, Anna Kjerstine Rosenmai, Joëlle Rüegg, Iva Sovadinová, Sabrina Tait, Mathew Van de Pette, Tamara Vanhaecke, Lucia Vergauwen, Eva Bay Wedebye, Elvis Genbo Xu, Terje Svingen
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2026-02-01
Serier:	Frontiers in Toxicology
Fag:	adverse outcome pathway (AOP) developmental toxicity endocrine disruption non-animal methods regulatory toxicology reproductive disorders
Online adgang:	https://www.frontiersin.org/articles/10.3389/ftox.2026.1736963/full
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