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BRAF Signaling Inhibition in Glioblastoma: Which Clinical Perspectives?

IDH-wild type (wt) glioblastoma (GB) accounts for approximately 90% of all GB and has a poor outcome. Surgery and adjuvant therapy with temozolomide and radiotherapy is the main therapeutic approach. Unfortunately, after relapse and progression, which occurs in most cases, there are very limited the...

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Detalles Bibliográficos
Principais autores: Victoria Bouchè, Giovanni Aldegheri, Carmine Antonio Donofrio, Antonio Fioravanti, Samuel Roberts-Thomson, Stephen B. Fox, Francesco Schettini, Daniele Generali
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Oncology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2021.772052/full
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