Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes

Abstract Tetracycline destructases (TDases) are flavin monooxygenases which can confer resistance to all generations of tetracycline antibiotics. The recent increase in the number and diversity of reported TDase sequences enables a deep investigation of the TDase sequence-structure-function landscap...

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Үндсэн зохиолчид:	Kevin S. Blake, Hirdesh Kumar, Anisha Loganathan, Emily E. Williford, Luke Diorio-Toth, Yao-Peng Xue, Wai Kwan Tang, Tayte P. Campbell, David D. Chong, Steven Angtuaco, Timothy A. Wencewicz, Niraj H. Tolia, Gautam Dantas
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2024-03-01
Цуврал:	Communications Biology
Онлайн хандалт:	https://doi.org/10.1038/s42003-024-06023-w
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!