The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells

Acute myeloid leukemia is an aggressive disease characterized by clonal proliferation and differentiation into immature hematopoietic cells of dysfunctional myeloid precursors. Accumulating evidence shows that CD34+CD38- leukemia stem cells (LSCs) are responsible for drug resistance, metastasis, and...

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Detalhes bibliográficos

Principais autores:	Dan-dan Xu, Ying Wang, Peng-jun Zhou, Shu-rong Qin, Rong Zhang, Yi Zhang, Xue Xue, Jianping Wang, Xia Wang, Hong-ce Chen, Xiao Wang, Yu-wei Pan, Li Zhang, Hai-zhao Yan, Qiu-ying Liu, Zhong Liu, Su-hong Chen, Hong-yuan Chen, Yi-fei Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-06-01
coleção:	Frontiers in Pharmacology
Assuntos:	Nanog IGF2 IGF1R proliferation leukemia stem cells
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2018.00687/full
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