TREC dynamics as a biomarker of naive T-cell homeostasis in traumatic brain injury: a longitudinal analysis

Post-traumatic immunosuppression complicates recovery from traumatic brain injury (TBI), increasing susceptibility to infection. Reliable biomarkers to assess immune status are required. We investigated the dynamics of T-cell receptor excision circles (TREC) and B-cell K-deleting recombination excis...

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Autori principali:	Darya A. Kashatnikova, Alesya S. Gracheva, Ekaterina V. Kalinina, Vladislav E. Zakharchenko, Tatyana N. Krylova, Maryam B. Khadzhieva, Sergey S. Larin, Artem N. Kuzovlev, Lyubov E. Salnikova
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-03-01
Serie:	Frontiers in Medicine
Soggetti:	age composite ‘severity/inflammation’ index linear mixed-effects models naive T-cell homeostasis TBI TREC/KREC dynamics
Accesso online:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1775886/full
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