Association of a pace of aging epigenetic clock with rate of cognitive decline in the Framingham Heart Study Offspring Cohort

Abstract INTRODUCTION The geroscience hypothesis proposes systemic biological aging is a root cause of cognitive decline. METHODS We analyzed Framingham Heart Study Offspring Cohort data (n = 2296; 46% male; baseline age M = 62, SD = 9, range = 25–101 y). We measured cognitive decline across two dec...

Descripción completa

Detalles Bibliográficos

Autores principales:	Micah J. Savin, Haoyang Wang, Heming Pei, Allison E. Aiello, Stephanie Assuras, Avshalom Caspi, Terrie E. Moffitt, Peter A. Muenning, Calen P. Ryan, Baoyi Shi, Yaakov Stern, Karen Sugden, Linda Valeri, Daniel W. Belsky
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2024-10-01
Colección:	Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Materias:	aging Alzheimer's disease and related dementias biological aging cognitive decline DunedinPACE epigenetic clocks
Acceso en línea:	https://doi.org/10.1002/dad2.70038
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!