Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Pediatric Coeliac Disease Patients Suggests Potential Pre-Seroconversion Markers

Celiac Disease (CeD) is a complex immune disorder involving villous atrophy in the small intestine that is triggered by gluten intake. Current CeD diagnosis is based on late-stage pathophysiological parameters such as detection of specific antibodies in blood and histochemical detection of villus at...

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Main Authors:	Aarón D. Ramírez-Sánchez, Xiaojing Chu, Rutger Modderman, Yvonne Kooy-Winkelaar, Sibylle Koletzko, Ilma R. Korponay-Szabó, Riccardo Troncone, Cisca Wijmenga, Luisa Mearin, Sebo Withoff, Iris H. Jonkers, Yang Li
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2022-03-01
Series:	Frontiers in Immunology
Subjects:	celiac disease scRNAseq PBMC differential gene expression pre-diagnostic biomarkers
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.843086/full
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