Design of Inhibitors That Target the Menin–Mixed-Lineage Leukemia Interaction

The prognosis of mixed-lineage leukemia (MLL) has remained a significant health concern, especially for infants. The minimal treatments available for this aggressive type of leukemia has been an ongoing problem. Chromosomal translocations of the KMT2A gene are known as MLL, which expresses MLL fusio...

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Autores principales:	Moses N. Arthur, Kristeen Bebla, Emmanuel Broni, Carolyn Ashley, Miriam Velazquez, Xianin Hua, Ravi Radhakrishnan, Samuel K. Kwofie, Whelton A. Miller
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2023-12-01
Colección:	Computation
Materias:	menin mixed-lineage leukemia molecular dynamics computer-aided drug design
Acceso en línea:	https://www.mdpi.com/2079-3197/12/1/3
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