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GFAP-NpHR mediated optogenetic inhibition of trigeminal nucleus caudalis attenuates hypersensitive behaviors and thalamic discharge attributed to infraorbital nerve constriction injury

Abstract The significance of hyperactive astrocytes in neuropathic pain is crucial. However, the association between medullary astrocytes and trigeminal neuralgia (TN)-related pain processing is unclear. Here, we examined how optogenetic inhibition of medullary astrocytes in the trigeminal nucleus c...

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Bibliografski detalji
Glavni autori: Elina KC, Jaisan Islam, Hyong Kyu Kim, Young Seok Park
Format: Artigo
Jezik:Inglês
Izdano: BMC 2023-10-01
Serija:The Journal of Headache and Pain
Teme:
Online pristup:https://doi.org/10.1186/s10194-023-01669-z
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