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Bicarbonate buffer enhances functional sperm selection compared to Zwitterionic buffers in sperm preparation

Abstract Sperm preparation media used in assisted reproductive technology (ART) laboratories typically contain single or combined buffers to maintain pH and support spermatozoa homeostasis. Concerns exist that zwitterionic buffers, such as 4-(2-hydroxyethyl)-1-piperazine ethane sulfonic acid (HEPES)...

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Principais autores: Huidrom Yaiphaba Meitei, Dhakshanya Predheepan, Shubhashree Uppangala, Vani Lakshmi R, Guruprasad Kalthur, Stefan Schlatt, Satish Kumar Adiga
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2026-03-01
coleção:Scientific Reports
Assuntos:
Assisted reproductive techniques
Infertility
Spermatozoa
Sperm wash
Sperm recovery
Swim-up technique
Acesso em linha:https://doi.org/10.1038/s41598-026-44733-9
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