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<italic toggle="yes">In Vivo</italic> Genome and Methylome Adaptation of <italic toggle="yes">cag</italic>-Negative <named-content content-type="genus-species">Helicobacter pylori</named-content> during Experimental Human Infection

ABSTRACT Multiple studies have demonstrated rapid bacterial genome evolution during chronic infection with Helicobacter pylori. In contrast, little was known about genetic changes during the first stages of infection, when selective pressure is likely to be highest. Using single-molecule, real-time...

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Principais autores: Iratxe Estibariz, Florent Ailloud, Sabrina Woltemate, Boyke Bunk, Cathrin Spröer, Jörg Overmann, Toni Aebischer, Thomas F. Meyer, Christine Josenhans, Sebastian Suerbaum
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020-08-01
coleção:mBio
Assuntos:
DNA methylation
Helicobacter pylori
adaptive mutations
genome analysis
SMRT sequencing
PacBio
Acesso em linha:https://journals.asm.org/doi/10.1128/mBio.01803-20
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