Adipose–Muscle Crosstalk in COPD Cachexia: Early Adipose Atrophy Drives Subsequent Muscle Wasting

ABSTRACT Background Chronic obstructive pulmonary disease (COPD) is frequently associated with cachexia, leading to poor prognoses and reduced quality of life. However, the mechanisms underlying adipose tissue atrophy, its pathological significance and its interaction with skeletal muscle remain poo...

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Detalles Bibliográficos

Principais autores:	Takashi Shimada, Shotaro Chubachi, Keisuke Nishikawa, Tetsuya Arai, Hideto Iizuka, Shiro Otake, Kaori Sakurai, Junko Hamamoto, Mamoru Sasaki, Tomoki Maetani, Naoya Tanabe, Katsunori Masaki, Hiroki Kabata, Jun Miyata, Yoshitake Yamada, Masahiro Jinzaki, Hidetoshi Nakamura, Koichiro Asano, Koichi Fukunaga
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2025-12-01
Series:	Journal of Cachexia, Sarcopenia and Muscle
Assuntos:	adipose tissue atrophy cachexia chronic obstructive pulmonary disease muscle wasting
Acceso en liña:	https://doi.org/10.1002/jcsm.70154
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