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Comparative Toxicotranscriptomics of Single Cell RNA-Seq and Conventional RNA-Seq in TCDD-Exposed Testicular Tissue

In this report, we compare the outcomes and limitations of two methods of transcriptomic inquiry on adult zebrafish testes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during sexual differentiation: conventional or bulk RNA-seq (bulk-seq) and single cell RNA sequencing (scRNA-seq) data. scR...

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Bibliografiske detaljer
Principais autores: Alex Haimbaugh, Danielle Meyer, Camille Akemann, Katherine Gurdziel, Tracie R. Baker
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-05-01
Serier:Frontiers in Toxicology
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Online adgang:https://www.frontiersin.org/articles/10.3389/ftox.2022.821116/full
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