IRF6 controls Epstein-Barr virus (EBV) lytic reactivation and differentiation in EBV-infected epithelial cells.

Latent Epstein-Barr virus (EBV) infection promotes undifferentiated nasopharyngeal carcinoma (NPC) and gastric carcinoma (GC), while EBV infection of normal differentiated oropharyngeal epithelial cells is lytic and kills the cell. Establishment of viral latency within epithelial cells is likely ess...

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Principais autores:	Stuart A Fogarty, Deo R Singh, Scott E Nelson, Maria E Calandranis, Yitao Zhang, Abigail S Pawelski, Alisha S Kansra, Sophie White, Shannon C Kenney
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2025-06-01
Colecção:	PLoS Pathogens
Acesso em linha:	https://doi.org/10.1371/journal.ppat.1013236
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