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Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion

Structural, functional, and molecular reorganization of denervated neural networks is often observed in neurological conditions. The loss of input is accompanied by homeostatic synaptic adaptations, which can affect the reorganization process. A major challenge of denervation-induced homeostatic pla...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Maximilian Lenz, Amelie Eichler, Pia Kruse, Phyllis Stöhr, Dimitrios Kleidonas, Christos Galanis, Han Lu, Andreas Vlachos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-04-01
Schriftenreihe:Frontiers in Molecular Neuroscience
Schlagworte:
entorhinal cortex lesion
Schaffer collateral lesion
transcriptome analysis
microglia
RNA oxidation
synaptic plasticity
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1148219/full
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