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Melatonin Alleviates Acute Sleep Deprivation-Induced Memory Loss in Mice by Suppressing Hippocampal Ferroptosis

Objectives: Memory decline caused by insufficient sleep is a critical public health issues and currently lacks effective treatments. This study objective was to explore alleviative effect of melatonin on sleep deprivation (SD)-induced deficiencies in learning and memory.Materials and Methods: A cont...

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Principais autores: Xintong Wang, Zixu Wang, Jing Cao, Yulan Dong, Yaoxing Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-07-01
Serier:Frontiers in Pharmacology
Fag:
sleep deprivation
ferroptosis
melatonin
hippocampus
memory loss
intracellular signaling pathway
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2021.708645/full
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