Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen® FFPE BRAF qPCR assay

Mutations in BRAF exon 15 lead to conformational changes in its activation loops, resulting in constitutively active BRAF proteins which are implicated in the development of several human cancer types. Different BRAF inhibitors have been developed and introduced in clinical practice. Identification...

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主要な著者:	Anna Lahn Sørensen, Mariann Guldmann-Christensen, Michael Børgesen, Rasmus Koefoed Petersen, Katharina Flugt, Julie Mejer Holmgaard Duelund, Majbritt Hauge Kyneb, Jan Lorenzen, Emma Pipó-Ollé, Samantha Epistolio, Alice Riva, Giulia Dazio, Elisabetta Merlo, Tine Meyer, Ulf Bech Christensen, Milo Frattini
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2023-01-01
シリーズ:	PLoS ONE
オンライン･アクセス:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910728/?tool=EBI
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