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Regulation of the Hypoxia-Inducible Factor (HIF) by Pro-Inflammatory Cytokines

Hypoxia and inflammation are frequently co-incidental features of the tissue microenvironment in a wide range of inflammatory diseases. While the impact of hypoxia on inflammatory pathways in immune cells has been well characterized, less is known about how inflammatory stimuli such as cytokines imp...

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Principais autores: Mykyta I. Malkov, Chee Teik Lee, Cormac T. Taylor
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-09-01
Serier:Cells
Fag:
hypoxia
HIF
HIF-1α
inflammation
TNF-α
IL-1β
Online adgang:https://www.mdpi.com/2073-4409/10/9/2340
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