Identity and stability assessment of BCG vaccine by multiplex PCR

Multiplex polymerase chain reaction method was used to assess the stability of 7 seed lots of a substrain Mycobacterium bovis BCG-1, Russia, used for the manufacture of BCG vaccine since 1948 till present. For performng PCR we used primers, matching 5 parts of the RD field and 1part of repeating ele...

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Autors principals:	D. T. Levi, Yu. I. Obukhov, N. V. Aleksandrova, R. A. Volkova, E. V. Elbert, M. V. Alvarez Figeroa, A. V. Prokopenko, R. I. Ludanniy
Format:	Artigo
Idioma:	Russo
Publicat:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-02-01
Col·lecció:	Биопрепараты: Профилактика, диагностика, лечение
Matèries:	посевная серия мультиплексная полимеразная реакция субштаммы бцж стабильнось подлинность seed lot multiplex polymerase reaction bcg substrains stability identity
Accés en línia:	https://www.biopreparations.ru/jour/article/view/41
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