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A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy

<p>Abstract</p> <p>Background</p> <p>At recurrence the use of nitrosoureas is widely-used as a therapeutic option for glioblastoma (GBM) patients. The efficacy of fotemustine (FTM) has been demonstrated in phase II clinical trials; however, these papers report a wide range of progression-free-surviv...

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Principais autores: Paccapelo Alessandro, Lolli Ivan, Fabrini Maria, Silvano Giovanni, Detti Beatrice, Perrone Franco, Savio Giuseppina, Santoni Matteo, Bonizzoni Erminio, Perrone Tania, Scoccianti Silvia
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2012-05-01
Serier:Journal of Translational Medicine
Fag:
Fotemustine
Nitrosourea
Recurrent-glioblastoma
Stupp-regimen
Temozolomide
Online adgang:http://www.translational-medicine.com/content/10/1/90
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