mGem: More than building blocks? Mitochondrial metabolism, viruses, and the host response to infection

ABSTRACT Beyond essential roles as central hubs integrating homeostatic cellular metabolism, mitochondria have emerged as critical determinants of infection outcomes. Mitochondrial activities, like MAVS signaling and the release of cytochrome c and mitochondrial DNA, drive host defenses. Across cell...

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Autors principals:	Jessica Alvarez, Dustin C. Hancks
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2026-06-01
Col·lecció:	mBio
Matèries:	mitochondria immunometabolism viral infection immune response OXPHOS mitochondrial dysfunction
Accés en línia:	https://journals.asm.org/doi/10.1128/mbio.02501-25
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