Differences in the Effectiveness of Uridine and <i>Liriope platyphylla</i> L. Between Complement Component 3 Deficiency- and Loperamide-Induced Constipation May Be Associated with the Alternative Regulation of the Cyclic Adenosine Monophosphate Downstream Signaling Pathway

<b>Background/Objectives</b>: Constipation can be induced in animal models through various factors such as loperamide (Lop) or complement component 3 (C3) deficiency. The effectiveness of therapeutic agents in the clinical management of constipation has been primarily evaluated within only one model...

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Autori principali:	Hee Jin Song, Eun Seo Park, Ji Eun Kim, Ayun Seol, Su Jeong Lim, Su Ha Wang, Ye Ryeong Kim, Ye Eun Ryu, So Hae Park, Jumin Park, Hyun Gu Kang, Dae Youn Hwang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-08-01
Serie:	Pharmaceuticals
Soggetti:	complement C3 loperamide constipation AELP uridine cAMP
Accesso online:	https://www.mdpi.com/1424-8247/18/9/1289
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