Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling.

Microglia and macrophages are recruited to sites of retinal degeneration where local cytokines and chemokines determine protective or neurotoxic microglia responses. Defining the role of Ccl2-Ccr2 and Cx3cl1-Cx3cr1 signalling for retinal pathology is of particular interest because of its potential r...

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Autori principali:	Ulrich F O Luhmann, Clemens A Lange, Scott Robbie, Peter M G Munro, Jill A Cowing, Hannah E J Armer, Vy Luong, Livia S Carvalho, Robert E MacLaren, Frederick W Fitzke, James W B Bainbridge, Robin R Ali
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2012-01-01
Serie:	PLoS ONE
Accesso online:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035551&type=printable
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Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling.

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