Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice
Humanized mouse models are valuable tools for investigating the human immune system in response to infection and injury. We have previously described the human immune system (HIS)-DRAGA mice (HLA-A2.HLA-DR4.Rag1KO.IL-2RgKO.NOD) generated by infusion of Human Leukocyte Antigen (HLA)-matched, human he...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2024-06-01
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| Serier: | Frontiers in Cellular and Infection Microbiology |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fcimb.2024.1367566/full |
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