Mesencephalic astrocyte-derived neurotrophic factor (MANF) prevents the neuroinflammation induced dopaminergic neurodegeneration

Background: The excessive activation of the microglia leads to the release of inflammatory factors that contribute to neuronal cell loss and neurodegeneration in Parkinson's Disease (PD). Mesencephalic astrocyte-derived neurotrophic factor (MANF) that belongs to a newly found neurotrophic factors (N...

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Detalhes bibliográficos

Principais autores:	Jing-Xing Zhang, Kai-Ge Zhou, Yan-Xin Yin, Ling-Jing Jin, Wei-Fang Tong, Jia Guo, Li-Hua Yu, Xian-Cheng Ye, Ming Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-01-01
coleção:	Experimental Gerontology
Assuntos:	Parkinson's disease (PD) Mesencephalic astrocyte-derived neurotrophic factor (MANF) Dopaminergic neurodegeneration Neuroinflammation Nrf-2 Microglia activation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0531556522003461
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